Management and prevention of cardiovascular hemorrhage associated with mediastinitis

Gregory Georgiade, Therese Anne Levan, James Anthony, Newland Oldham, Hochberg Julio, Carmello Milano, Edmond Ritter

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Objective: To elucidate the causes of cardiovascular hemorrhage associated with mediastinitis and to review recommendations for prevention and treatment. Summary Background Data: Mediastinal debridement with immediate or early coverage using healthy, vascularized tissue has lead to greatly reduced morbidity and mortality for patients with mediastinitis. Myocardial hemorrhage has been anecdotally reported. Patients and Methods: Over a 36-month period, 7 patients developed massive cardiovascular bleeding after undergoing debridement for poststernotomy mediastinitis. Causes included puncture or erosion by a sternal edge in three and tearing at the myocardial-sternal interface in four. Results: Five patients survived and remain infection-free at an average of 24 months of follow-up. In these patients, ventricular defects were closed with pledgeted sutures and muscle transposition was used concomitantly to reinforce the repair. This involved a slide of the left pectoralis major muscle and turnover of the right pectoralis in three patients, bilateral sliding in one patient, and bilateral pectoralis and an omental flap in one patient who required additional coverage of the lower mediastinum. Conclusions: When a patient who has undergone mediastinal debridement shows evidence of significant bleeding, we recommend application of pressure for control of hemorrhage, expeditious return to an operating room with available cardiopulmonary bypass, and immediate muscle coverage with healthy, well-vascularized tissue. Finally, early sternectomy might largely prevent this life-threatening complication.

Original languageEnglish (US)
Pages (from-to)145-150
Number of pages6
JournalAnnals of surgery
Issue number1
StatePublished - Jan 1998
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Management and prevention of cardiovascular hemorrhage associated with mediastinitis'. Together they form a unique fingerprint.

Cite this