Medical and psychiatric comorbidities: Complicating treatment expectations

Brian J. Miller; Peter F. Buckley

doi:10.1007/978-3-642-45257-4_4

Medical and psychiatric comorbidities: Complicating treatment expectations

Brian J. Miller
, Peter F. Buckley

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Upon all outcomes, premature mortality is a profound consequence of medical and psychiatric (especially depression with suicidality) comorbidities. Additionally, obesity and metabolic disturbances substantially complicate the selection and duration of trial of subsequent antipsychotic medications. This is most pronounced with respect to clozapine, wherein obesity and metabolic dysfunction now predominate and powerful influence the use of this drug as well as adjunctive therapies.

Original language	English (US)
Title of host publication	Treatment-Refractory Schizophrenia
Subtitle of host publication	A Clinical Conundrum
Publisher	Springer Berlin Heidelberg
Pages	45-64
Number of pages	20
ISBN (Electronic)	9783642452574
ISBN (Print)	9783642452567
DOIs	https://doi.org/10.1007/978-3-642-45257-4_4
State	Published - Jan 1 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-642-45257-4_4

Cite this

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AB - Upon all outcomes, premature mortality is a profound consequence of medical and psychiatric (especially depression with suicidality) comorbidities. Additionally, obesity and metabolic disturbances substantially complicate the selection and duration of trial of subsequent antipsychotic medications. This is most pronounced with respect to clozapine, wherein obesity and metabolic dysfunction now predominate and powerful influence the use of this drug as well as adjunctive therapies.

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ER -

Medical and psychiatric comorbidities: Complicating treatment expectations

Abstract

UN SDGs

ASJC Scopus subject areas

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