Metrologic Evaluation of the Surface of White MTA After the Use of Two Endodontic Irrigants

Jack B. Smith, Robert J. Loushine, R. Norman Weller, Frederick A. Rueggeberg, Gary M. Whitford, David H. Pashley, Franklin R. Tay

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


This study examined the effects of calcium-depleting endodontic irrigants, ethylenediamine tetra-acetic acid (EDTA) and BioPure MTAD, on the dissolution, surface characteristics, and ultrastructural characteristics of white mineral trioxide aggregate (MTA). The latter was mixed in a 0.35 water-cement ratio, condensed into cylindrical wells created in Plexiglas platforms, and allowed to harden completely before initial treatment with 1.3% NaOCl and final treatments with either 17% EDTA for 5 minutes, or BioPure MTAD for 1, 3, or 5 minutes. Analysis of the mean depths of material removed using three-dimensional profilometry revealed significantly more material removed by BioPure MTAD. Although these minor depth changes (<10 μm) are unlikely to cause clinical concern, the BioPure MTAD-treated MTA surfaces exhibited higher surface roughness and with more calcium extracted when compared with EDTA treatment. Decomposition of particle-binding hydration phases by acid corrosion raises potential concern on the strength and sealing properties of MTA-repaired perforations following final irrigation by BioPure MTAD.

Original languageEnglish (US)
Pages (from-to)463-467
Number of pages5
JournalJournal of endodontics
Issue number4
StatePublished - Apr 2007


  • 3-D profilometry
  • BioPure MTAD
  • EDTA
  • atomic absorption spectroscopy
  • dissolution
  • mineral trioxide aggregate
  • scanning electron microscopy
  • surface corrosion

ASJC Scopus subject areas

  • Dentistry(all)


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