Mitochondrial fission and fusion

Research output: Contribution to journalArticlepeer-review

133 Scopus citations


Mitochondrial fission and fusion have been recognized as critical processes in the health of mitochondria and cells. Two decades of studies have generated a great deal of information about mitochondrial fission and fusion; however, still much needs to be understood for the basic molecular mechanisms of these important cellular processes. The core protein factors for mitochondrial fission and fusion are dynamin proteins that possess membrane-remodeling properties. This short review covers a recent development and understanding of the mechanisms by which these mechanochemical enzymes mediate mitochondrial fission and fusion.

Original languageEnglish (US)
Pages (from-to)1725-1735
Number of pages11
JournalBiochemical Society Transactions
Issue number6
StatePublished - Dec 15 2016

ASJC Scopus subject areas

  • Biochemistry


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