MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

  • Juliana M. Benito
  • , Laura Godfrey
  • , Kensuke Kojima
  • , Leah Hogdal
  • , Mark Wunderlich
  • , Huimin Geng
  • , Isabel Marzo
  • , Karine G. Harutyunyan
  • , Leonard Golfman
  • , Phillip North
  • , Jon Kerry
  • , Erica Ballabio
  • , Triona Ní Chonghaile
  • , Oscar Gonzalo
  • , Yihua Qiu
  • , Irmela Jeremias
  • , La Kiesha Debose
  • , Eric O'Brien
  • , Helen Ma
  • , Ping Zhou
  • Rodrigo Jacamo, Eugene Park, Kevin R. Coombes, Nianxiang Zhang, Deborah A. Thomas, Susan O'Brien, Hagop M. Kantarjian, Joel D. Leverson, Steven M. Kornblau, Michael Andreeff, Markus Müschen, Patrick A. Zweidler-McKay, James C. Mulloy, Anthony Letai, Thomas A. Milne, Marina Konopleva

Research output: Contribution to journalArticlepeer-review

128 Scopus citations

Fingerprint

Dive into the research topics of 'MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199'. Together they form a unique fingerprint.

Keyphrases

Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science