Modified diffusion models for steady-state broadband reflectance with a needle-like optic probe

H. Liu; M. Johns; C. A. Giller

doi:10.1117/12.434472

Modified diffusion models for steady-state broadband reflectance with a needle-like optic probe

H. Liu
, M. Johns
, C. A. Giller

Research output: Contribution to journal › Conference article › peer-review

2 Scopus citations

Abstract

Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500-590 nm) reflectance with source-detector separations of 0.125-0.25 mm and 0.25-1.0 mm. For the former case, the major modifications are D = 1/3μ_s' and z₀ = 1/μ_s'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.

Original language	English (US)
Pages (from-to)	76-81
Number of pages	6
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	4250
DOIs	https://doi.org/10.1117/12.434472
State	Published - 2001
Externally published	Yes
Event	Optical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States Duration: Jan 21 2001 → Jan 23 2001

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.434472

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title = "Modified diffusion models for steady-state broadband reflectance with a needle-like optic probe",

abstract = "Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500-590 nm) reflectance with source-detector separations of 0.125-0.25 mm and 0.25-1.0 mm. For the former case, the major modifications are D = 1/3μs' and z0 = 1/μs'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12\% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.",

author = "H. Liu and M. Johns and Giller, \{C. A.\}",

year = "2001",

doi = "10.1117/12.434472",

language = "English (US)",

volume = "4250",

pages = "76--81",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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publisher = "SPIE",

note = "Optical Tomography and Spectroscopy of Tissue IV ; Conference date: 21-01-2001 Through 23-01-2001",

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TY - JOUR

T1 - Modified diffusion models for steady-state broadband reflectance with a needle-like optic probe

AU - Liu, H.

AU - Johns, M.

AU - Giller, C. A.

PY - 2001

Y1 - 2001

N2 - Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500-590 nm) reflectance with source-detector separations of 0.125-0.25 mm and 0.25-1.0 mm. For the former case, the major modifications are D = 1/3μs' and z0 = 1/μs'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.

AB - Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500-590 nm) reflectance with source-detector separations of 0.125-0.25 mm and 0.25-1.0 mm. For the former case, the major modifications are D = 1/3μs' and z0 = 1/μs'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.

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DO - 10.1117/12.434472

M3 - Conference article

AN - SCOPUS:0034866960

SN - 0277-786X

VL - 4250

SP - 76

EP - 81

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Optical Tomography and Spectroscopy of Tissue IV

Y2 - 21 January 2001 through 23 January 2001

ER -

Modified diffusion models for steady-state broadband reflectance with a needle-like optic probe

Abstract

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