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Monte Carlo simulation of Temperature Distribution for Skin Tissue During Photobiomodulation

  • Weibing Yang
  • , Dennis Sourvanos
  • , Andreea Dimofte
  • , Theresa M. Busch
  • , Praveen Arany
  • , Todd Schoenbaum
  • , Joseph P. Fiorellini
  • , Timothy C. Zhu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Photobiomodulation (PBM) is a non-invasive therapeutic technique that uses low-level laser to stimulate cellular function and promote healing. By delivering light at specific wavelengths, PBM interacts with cellular components to enhance tissue repair, reduce inflammation, and modulate pain. Temperature distribution during PBM treatment is a crucial factor in optimizing treatment protocols. The optical properties of the tissue, such as scattering and absorption, directly influence how heat is generated and distributed, impacting the effectiveness of PBM therapy. This study utilizes Monte Carlo (MC) simulations to model temperature distribution within simulated skin tissue during PBM treatment. By employing MC simulations in MATLAB, we investigate how variations in the tissue's scattering and absorption coefficients for epidermis, dermis and blood vessels impact the resulting temperature distribution. Understanding these thermal effects is crucial for optimizing PBM treatments. The tissue model is designed to simulate the complex interactions between light and biological tissue, capturing how light scattering and absorption affect heat generation and propagation. Temperature distribution within the simplified skin tissue is simulated under various conditions to evaluate the influence of different optical properties. The results of this simulation provide valuable insights into how adjustments to the PBM parameters can optimize therapeutic outcomes, ensuring effective treatment while minimizing the risk of thermal damage. This work aims to contribute to the refinement of PBM treatment protocols by offering a deeper understanding of the thermal dynamics in response to varying tissue optical properties. The findings could guide the development of more precise and personalized PBM therapies.

Original languageEnglish (US)
Title of host publicationMechanisms of Photobiomodulation Therapy XIX
EditorsAnn Liebert, Jeri-Anne Lyons, James D. Carroll
PublisherSPIE
ISBN (Electronic)9781510683426
DOIs
StatePublished - 2025
EventMechanisms of Photobiomodulation Therapy XIX 2025 - San Francisco, United States
Duration: Jan 25 2025Jan 26 2025

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume13297
ISSN (Print)1605-7422

Conference

ConferenceMechanisms of Photobiomodulation Therapy XIX 2025
Country/TerritoryUnited States
CitySan Francisco
Period1/25/251/26/25

Keywords

  • Photobiomodulation (PBM)
  • monte carlo simulation
  • skin tissue
  • temperature distribution
  • tissue optical properties

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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