Magnetoencephalography (MEG) was used to evaluate 40candidates for seizure surgery thought to have foci outside the anteromesial temporal lobe. Of 29 cases with electrographic data suggesting a convexity focus. MEG spikes were recorded from 28. In 21. MEG and electrographic data were localized to the same area. Invasive studies were, or could have been, avoided in 13 cases based on MEG and other noninvasive data. MEG was not of localizing value in 4 orbitofrontal or 7-depth-nonlocalized cases. Seventeen patients with MEG epileptiform data have had postoperative follow-up. Eight of 13 with electrographic and MEG data localized to the same area are seizure free. None of 4 with spatial discordance of MEG and electrographic data are seizure free.
- MEG/EEG agreement
- Single equivalent current dipole
ASJC Scopus subject areas
- Clinical Neurology