Abstract
Management of research-animal colonies is vital for lab productivity in preclinical research. Labs often rely on inefficient paper-based or spreadsheet-based methods to manage animal colonies. Dedicated software-based solutions are generally expensive and many lack remote access. Currently available open-source alternatives are difficult to implement and deploy. These solutions also do not have the capability to track ambient variables that affect colony well-being. We built MyVivarium, an open-source database management web application to address these gaps. MyVivarium can be easily deployed to the cloud and sustained for a cost comparable to starting and maintaining a lab website. Using MyVivarium, lab members can collaboratively track individual animals within a database. Physical identities of cages map onto the database using QR codes, enabling quick and easy record-keeping on mobile devices. Lab administrators can assign tasks to users with reminders for experiments or cage maintenance. Finally, we designed a low-cost system to sense ambient humidity, temperature, vivarium worker activity, and room illuminance. These data are then sent to MyVivarium in realtime providing information relevant to colony well-being. Taken together, MyVivarium is a novel, open-source, cloud-based application template that provides a low-cost, simple, and efficient way to digitally manage research-animal colonies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 612-623 |
| Number of pages | 12 |
| Journal | Computational and Structural Biotechnology Journal |
| Volume | 27 |
| DOIs | |
| State | Published - Jan 2025 |
Keywords
- Biological database
- IoT sensors
- Mouse facility
- Open-source technology
ASJC Scopus subject areas
- Biotechnology
- Structural Biology
- Biophysics
- Biochemistry
- Genetics
- Computer Science Applications
Fingerprint
Dive into the research topics of 'MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS