Near-Drowning Complicated by Brain Abscess due to Petriellidium boydii

John F. Fisher, Smith Shadomy, J. Robert Teabeaut, Janet Woodward, Gene E. Michaels, Mark A. Newman, Elizabeth White, Paul Cook, Annette Seagraves, Farivar Yaghmai, J. Peter Rissing

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55 Scopus citations


Extracutaneous infection from Petriellidium boydii is an unusual occurrence despite the ubiquity of the organism in nature. Central nervous system infection by this organism is extremely rare, only seven previous reports having been found. The rarity of this manifestation prompted the report of a brain abscess occurring in a previously healthy youth after a near-drowning. The source of the infection was likely to have been the river water at the accident site, from which P boydii was isolated. Although previous in vitro susceptibility data and failure of amphotericin B therapy in a similar infection suggested miconazole treatment might be beneficial, the organism causing the brain abscess was resistant to miconazole and amphotericin B. This report emphasizes the urgent need for safer and more predictably effective alternatives to currently available antifungal agents.

Original languageEnglish (US)
Pages (from-to)511-513
Number of pages3
JournalArchives of Neurology
Issue number8
StatePublished - Aug 1982

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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