@inbook{01680c4e7ab94d74b0e8eda0a467f241,
title = "New insights into leukocyte recruitment by intravital microscopy",
abstract = "Leukocyte recruitment to sites of inflammation requires adhesion to and transmigration through the blood vessel wall. Recent progress in optical equipment and new genetic and molecular tools have revealed additional steps in the leukocyte adhesion cascade beyond rolling, adhesion, and transmigration. In vivo studies using intravital microscopy (IVM) were essential for the discovery of slow rolling, postadhesion strengthing, intraluminal crawling, and different routes of transmigration. IVM revealed unique features of leukocyte recruitment in different organs. This review focuses on insights into the leukocyte adhesion cascade gained by IVM.",
author = "Alexander Zarbock and Klaus Ley",
note = "Funding Information: Supported by grants from Deutsche Forschungsgemeinschaft (AZ 428/2–1 and AZ 428/3-1 to A.Z.) and by grants from the National Institutes of Health to K.L.",
year = "2009",
doi = "10.1007/978-3-540-93864-4\_6",
language = "English (US)",
isbn = "9783540938620",
series = "Current Topics in Microbiology and Immunology",
publisher = "Springer Verlag",
number = "1",
pages = "129--152",
booktitle = "Visualizing Immunity",
edition = "1",
}