Nicotine decreases bradykinesia-rigidity in haloperidol-treated patients with schizophrenia

Yen Kuang Yang, Leann Nelson, Lakshmi Kamaraju, William Wilson, Joseph P. McEvoy

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

We applied nicotine 21 mg and matching placebo transdermal patches to thirty haloperidol-treated patients with schizophrenia who smoked. Clinical assessments of bradykinesia-rigidity were lower during nicotine patch administration than during placebo patch administration.

Original languageEnglish (US)
Pages (from-to)684-686
Number of pages3
JournalNeuropsychopharmacology
Volume27
Issue number4
DOIs
StatePublished - Oct 2002
Externally publishedYes

Keywords

  • Bradykinesia
  • Haloperidol
  • Nicotine
  • Rigidity
  • Schizophrenia
  • Tremor

ASJC Scopus subject areas

  • Pharmacology
  • Psychiatry and Mental health

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