Nodular regenerative hyperplasia of the liver with portal vein thrombosis and hyperplasia of the adrenal gland

Tohru Fukai; Hiromi Ishibashi; Toshiro Noda; Kazufumi Dohmen; Jiro Kudo; Seiho Nagafuchi; Katsuo Sueishi; Taku Yamasaki; Hiroto Sameshima

doi:10.1007/BF02775072

Nodular regenerative hyperplasia of the liver with portal vein thrombosis and hyperplasia of the adrenal gland

Tohru Fukai, Hiromi Ishibashi, Toshiro Noda, Kazufumi Dohmen, Jiro Kudo, Seiho Nagafuchi, Katsuo Sueishi, Taku Yamasaki, Hiroto Sameshima

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Nodular regenerative hyperplasia (NRH) of the liver is an uncommon entity of unknown origin and pathogenesis. We report here a case of NRH of the liver which was associated with portal vein thrombosis and adrenal hyperplasia. A 48-year-old man who was admitted for further examination of portal hypertension and splenomegaly, died of acute myocardial infarction. Autopsy revealed an enlarged heart with occluded coronary arteries and fresh multiple necrosis in the myocardium. The spleen and the liver were enlarged. In the liver diffusely distributed nodules of regenerative hyperplasia were noted. Organized thrombi of the portal vein and adenomatous hyperplasia of the left adrenal gland were also noted. Antinuclear antibody was positive in the serum.

Original language	English (US)
Pages (from-to)	108-114
Number of pages	7
Journal	Gastroenterologia Japonica
Volume	27
Issue number	1
DOIs	https://doi.org/10.1007/BF02775072
State	Published - Feb 1992
Externally published	Yes

Keywords

adrenal gland hyperplasia
antinuclear antibody
nodular regenerative hyperplasia
portal vein thrombosis

ASJC Scopus subject areas

Gastroenterology

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10.1007/BF02775072

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title = "Nodular regenerative hyperplasia of the liver with portal vein thrombosis and hyperplasia of the adrenal gland",

abstract = "Nodular regenerative hyperplasia (NRH) of the liver is an uncommon entity of unknown origin and pathogenesis. We report here a case of NRH of the liver which was associated with portal vein thrombosis and adrenal hyperplasia. A 48-year-old man who was admitted for further examination of portal hypertension and splenomegaly, died of acute myocardial infarction. Autopsy revealed an enlarged heart with occluded coronary arteries and fresh multiple necrosis in the myocardium. The spleen and the liver were enlarged. In the liver diffusely distributed nodules of regenerative hyperplasia were noted. Organized thrombi of the portal vein and adenomatous hyperplasia of the left adrenal gland were also noted. Antinuclear antibody was positive in the serum.",

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T1 - Nodular regenerative hyperplasia of the liver with portal vein thrombosis and hyperplasia of the adrenal gland

AU - Fukai, Tohru

AU - Ishibashi, Hiromi

AU - Noda, Toshiro

AU - Dohmen, Kazufumi

AU - Kudo, Jiro

AU - Nagafuchi, Seiho

AU - Sueishi, Katsuo

AU - Yamasaki, Taku

AU - Sameshima, Hiroto

PY - 1992/2

Y1 - 1992/2

N2 - Nodular regenerative hyperplasia (NRH) of the liver is an uncommon entity of unknown origin and pathogenesis. We report here a case of NRH of the liver which was associated with portal vein thrombosis and adrenal hyperplasia. A 48-year-old man who was admitted for further examination of portal hypertension and splenomegaly, died of acute myocardial infarction. Autopsy revealed an enlarged heart with occluded coronary arteries and fresh multiple necrosis in the myocardium. The spleen and the liver were enlarged. In the liver diffusely distributed nodules of regenerative hyperplasia were noted. Organized thrombi of the portal vein and adenomatous hyperplasia of the left adrenal gland were also noted. Antinuclear antibody was positive in the serum.

AB - Nodular regenerative hyperplasia (NRH) of the liver is an uncommon entity of unknown origin and pathogenesis. We report here a case of NRH of the liver which was associated with portal vein thrombosis and adrenal hyperplasia. A 48-year-old man who was admitted for further examination of portal hypertension and splenomegaly, died of acute myocardial infarction. Autopsy revealed an enlarged heart with occluded coronary arteries and fresh multiple necrosis in the myocardium. The spleen and the liver were enlarged. In the liver diffusely distributed nodules of regenerative hyperplasia were noted. Organized thrombi of the portal vein and adenomatous hyperplasia of the left adrenal gland were also noted. Antinuclear antibody was positive in the serum.

KW - adrenal gland hyperplasia

KW - antinuclear antibody

KW - nodular regenerative hyperplasia

KW - portal vein thrombosis

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Nodular regenerative hyperplasia of the liver with portal vein thrombosis and hyperplasia of the adrenal gland

Abstract

Keywords

ASJC Scopus subject areas

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