Nonspecific motility disorders, irritable esophagus, and chest pain

Anne Lund Krarup, Donghua Liao, Hans Gregersen, Asbjørn Mohr Drewes, Reza A. Hejazi, Richard W. Mccallum, Kenneth J. Vega, Marzio Frazzoni, Leonardo Frazzoni, John O. Clarke, Sami R. Achem

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


This paper presents commentaries on whether Starling's law applies to the esophagus; whether erythromycin affects esophageal motility; the relationship between hypertensive lower esophageal sphincter and vigorous achalasia; whether ethnic- and gender-based norms affect diagnosis and treatment of esophageal motor disorders; health care and epidemiology of chest pain; whether normal pH excludes esophageal pain; the role of high-resolution manometry in noncardiac chest pain; whether pH-impedance should be included in the evaluation of noncardiac chest pain; whether there are there alternative therapeutic options to PPI for treating noncardiac chest pain; and the usefulness of psychological treatment and alternative medicine in noncardiac chest pain.

Original languageEnglish (US)
Pages (from-to)96-109
Number of pages14
JournalAnnals of the New York Academy of Sciences
Issue number1
StatePublished - Oct 2013
Externally publishedYes


  • Achalasia
  • Antidepressant
  • NCCP
  • PPI

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science


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