TY - JOUR
T1 - Opioid Rotation and Conversion Ratios Used by Palliative Care Professionals
T2 - An International Survey
AU - Reddy, Akhila
AU - Sinclair, Christian
AU - Crawford, Gregory B.
AU - Mcpherson, Mary Lynn
AU - Mercadante, Sebastiano
AU - Hui, David
AU - Haider, Ali
AU - Arthur, Joseph
AU - Tanco, Kimberson
AU - Dalal, Shalini
AU - Dev, Rony
AU - Amaram-Davila, Jaya
AU - Adile, Claudio
AU - Liu, Diane
AU - Schuler, Ulrich
AU - Jammi, Sheetal
AU - Shelal, Zeena
AU - Del Fabbro, Egidio
AU - Davis, Mellar
AU - Bruera, Eduardo
N1 - Publisher Copyright:
© Copyright 2022, Mary Ann Liebert, Inc., publishers 2022.
PY - 2022/10/1
Y1 - 2022/10/1
N2 - Background: The opioid rotation ratios (ORRs) and conversion ratios (CRs) used worldwide among palliative care (PC) professionals to perform opioid rotations (ORs) and route conversions may have a wide variation. Methods: We surveyed PC professionals on opioid ratios used through email to the Multinational Association of Supportive Care in Cancer's PC study group and Twitter and Facebook posts between September and November 2020. Results: We received 370 responses from respondents from 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39 (11%) pharmacists, and 9 respondents did not report their profession. There were statistically significant variations in median CR from intravenous (IV) to oral morphine (2-3), IV to oral hydromorphone (2-4.5), ORR from IV hydromorphone to oral morphine (10-20), and ORR from transdermal fentanyl mcg/hour to oral morphine (2-3.5) across various groups. Conclusion: This survey highlights the wide variation in ORRs and CRs among PC clinicians worldwide and the need for further research to standardize practice.
AB - Background: The opioid rotation ratios (ORRs) and conversion ratios (CRs) used worldwide among palliative care (PC) professionals to perform opioid rotations (ORs) and route conversions may have a wide variation. Methods: We surveyed PC professionals on opioid ratios used through email to the Multinational Association of Supportive Care in Cancer's PC study group and Twitter and Facebook posts between September and November 2020. Results: We received 370 responses from respondents from 53 countries: 276 (76%) were physicians, 46 (13%) advanced practice providers, 39 (11%) pharmacists, and 9 respondents did not report their profession. There were statistically significant variations in median CR from intravenous (IV) to oral morphine (2-3), IV to oral hydromorphone (2-4.5), ORR from IV hydromorphone to oral morphine (10-20), and ORR from transdermal fentanyl mcg/hour to oral morphine (2-3.5) across various groups. Conclusion: This survey highlights the wide variation in ORRs and CRs among PC clinicians worldwide and the need for further research to standardize practice.
KW - cancer pain
KW - conversion ratio
KW - morphine equivalent daily dose
KW - opioid rotation
KW - opioid rotation ratio
KW - palliative care
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U2 - 10.1089/jpm.2022.0266
DO - 10.1089/jpm.2022.0266
M3 - Article
C2 - 35930252
AN - SCOPUS:85138746207
SN - 1096-6218
VL - 25
SP - 1557
EP - 1562
JO - Journal of Palliative Medicine
JF - Journal of Palliative Medicine
IS - 10
ER -