TY - JOUR
T1 - Osteosarcoma of the jaws
T2 - Report of 3 cases with emphasis on the early clinical and radiographic signs
AU - Charmelo-Silva, Scarlet
AU - Buchanan, Allison
AU - Kalathingal, Sajitha
AU - Abdelsayed, Rafik
N1 - Publisher Copyright:
© 2021
PY - 2022/2
Y1 - 2022/2
N2 - Osteosarcoma is the most common primary malignancy of the jaws and is treated by radical surgical resection. Early detection is crucial because removing the lesion with clean margins contributes most to the outcome. We present 3 cases of osteosarcoma occurring in the interradicular region of the mandible, 2 of which were thought to represent nonmalignant processes upon initial presentation. All 3 demonstrated early but significant clinical and radiographic features indicative of the malignant disease process. Radiographically, these cases had in common unilateral periodontal ligament (PDL) space widening, displacement of teeth, and growth of the crestal bone. Clinically, all 3 cases presented with a painless intraoral swelling. Case 1: a 20-year-old African American man presented with swelling and loose teeth with a duration of 1.5 months. Histopathologic diagnosis of osteoblastic osteosarcoma, high grade, was made. Case 2: a 75-year-old White man presented with a 2 × 2 cm expansile lesion with a duration of 2 months. Histopathologic diagnosis of chondroblastic osteosarcoma was made. Case 3: a 63-year-old White woman presented with a 5- to 6-mm lesion with a duration of at least 1 month. Histopathologic diagnosis of chondroblastic osteosarcoma was made. All 3 cases were treated with wide surgical resection.
AB - Osteosarcoma is the most common primary malignancy of the jaws and is treated by radical surgical resection. Early detection is crucial because removing the lesion with clean margins contributes most to the outcome. We present 3 cases of osteosarcoma occurring in the interradicular region of the mandible, 2 of which were thought to represent nonmalignant processes upon initial presentation. All 3 demonstrated early but significant clinical and radiographic features indicative of the malignant disease process. Radiographically, these cases had in common unilateral periodontal ligament (PDL) space widening, displacement of teeth, and growth of the crestal bone. Clinically, all 3 cases presented with a painless intraoral swelling. Case 1: a 20-year-old African American man presented with swelling and loose teeth with a duration of 1.5 months. Histopathologic diagnosis of osteoblastic osteosarcoma, high grade, was made. Case 2: a 75-year-old White man presented with a 2 × 2 cm expansile lesion with a duration of 2 months. Histopathologic diagnosis of chondroblastic osteosarcoma was made. Case 3: a 63-year-old White woman presented with a 5- to 6-mm lesion with a duration of at least 1 month. Histopathologic diagnosis of chondroblastic osteosarcoma was made. All 3 cases were treated with wide surgical resection.
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U2 - 10.1016/j.oooo.2021.09.001
DO - 10.1016/j.oooo.2021.09.001
M3 - Article
C2 - 34758943
AN - SCOPUS:85118851538
SN - 2212-4403
VL - 133
SP - e57-e62
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
IS - 2
ER -