TY - JOUR
T1 - Ovarian surgery on the rabbit
T2 - Effect of cortex closure on adhesion formation and ovarian function
AU - Meyer, W. R.
AU - Grainger, D. A.
AU - DeCherney, A. H.
AU - Lachs, M. S.
AU - Diamond, M. P.
PY - 1991
Y1 - 1991
N2 - Surgical reapproximation of serosal surfaces in an attempt to reduce adhesiogenesis remains a controversial issue. For the reproductive gynecologist, this tenet is especially appropriate to the ovarian cortical surface. Using a rabbit model (n = 22), an ovarian unipolar cautery incision was created, and surgical closure versus nonclosure was evaluated. Closure with continuous 6-0 polyglactin resulted in a significant increase in the degree of ovarian adhesion envelopment versus nonclosure (1.8±0.2 vs. 0.9±0.2, P < .01). Surgical closure also resulted in a significant increase in the vascularity of the adhesions (P < .05). Despite the increase in adhesion formation, ovarian function, as determined by the mean number of corpora lutea, pregnancies and the nidation index, was not different in sutured ovaries, unsutured ovaries or nonsurgically treated controls.
AB - Surgical reapproximation of serosal surfaces in an attempt to reduce adhesiogenesis remains a controversial issue. For the reproductive gynecologist, this tenet is especially appropriate to the ovarian cortical surface. Using a rabbit model (n = 22), an ovarian unipolar cautery incision was created, and surgical closure versus nonclosure was evaluated. Closure with continuous 6-0 polyglactin resulted in a significant increase in the degree of ovarian adhesion envelopment versus nonclosure (1.8±0.2 vs. 0.9±0.2, P < .01). Surgical closure also resulted in a significant increase in the vascularity of the adhesions (P < .05). Despite the increase in adhesion formation, ovarian function, as determined by the mean number of corpora lutea, pregnancies and the nidation index, was not different in sutured ovaries, unsutured ovaries or nonsurgically treated controls.
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M3 - Article
C2 - 1774725
AN - SCOPUS:0025740922
SN - 0024-7758
VL - 36
SP - 639
EP - 643
JO - Journal of Reproductive Medicine for the Obstetrician and Gynecologist
JF - Journal of Reproductive Medicine for the Obstetrician and Gynecologist
IS - 9
ER -