Ovulation induction with human menopausal gonadotropins

M. P. Diamond, A. Colston Wentz

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations


This review has summarized the evolution of hMG stimulation of ovulation in amenorrheic individuals, its monitoring, and its complications. Based on the principles learned from these individuals, use of hMG has now extended to women with cervical mucus deficiencies or luteal phase defects, as well as in vitro fertilization. Recommendations regarding the use of hMG at the current time when assessment by both serum E2 and ultrasound are available have been made. Briefly, it is suggested that an 'E2 window' of at least 1000 pg/ml be achieved over the course of a 9- to 12-day follicular phase. Furthermore, assessment of these monitoring modalities should be made in combination in order that findings from one modality alone not be allowed to initiate premature hCG administration.

Original languageEnglish (US)
Pages (from-to)480-490
Number of pages11
JournalObstetrical and Gynecological Survey
Issue number8
StatePublished - Dec 1 1986
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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