Periodontal repair in intrabony defects treated with a calcium carbonate implant and guided tissue regeneration

Chong Kwan Kim, Eun Jeong Choi, Kyoo Sung Cho, Jung Kiu Chai, Ulf M E Wikesjö

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66 Scopus citations

Abstract

CLINICAL OUTCOME FOLLOWING the concurrent use of a porous resorbable calcium carbonate (CC) implant and guided tissue regeneration (GTR) in intrabony periodontal defects was evaluated in a randomized four-treatment parallel arm study. Eighty (80) patients, each contributing one interproximal intrabony defect, were assigned to the four treatments (20 patients per treatment) including the CC implant and GTR (CC+GTR), GTR alone (GTR control), CC implant alone (CC control), and gingival flap surgery alone (GFS control). Fourteen patients treated with CC+GTR, 19 patients treated with the GTR control, 13 patients treated with the CC control, and 18 patients treated with the GFS control completed the study. Clinical healing was evaluated 6 months postsurgery and included changes in probing depth, clinical attachment level, probing bone level, and gingival recession. Postsurgery probing depth reduction was 4.5 ± 1.7 mm (CC+GTR; P < 0.01), 4.8 ± 1.8 mm (GTR; P < 0.01), 3.7 ± 2.2 mm (CC; P < 0.01), and 3.3 ± 1.6 mm (GFS; P < 0.01). Clinical attachment gain amounted to 3.3 ± 1.4 mm (CC+GTR; P < 0.01), 4.0 ± 2.1 mm (GTR; P < 0.01), 3.0 ± 2.4 mm (CC; P < 0.01), and 2.0 ± 1.7 mm (GFS; P < 0.01). The CC+GTR and GTR treatments exhibited significantly greater improvements compared to GFS (P < 0.05). Postsurgery probing bone level gain amounted to 4.0 ± 1.7 mm (CC+GTR; P < 0.01), 4.1 ± 1.5 mm (GTR; P < 0.01), 4.0 ± 2.2 mm (CC; P < 0.01), and 0.5 ± 2.0 mm (GFS; P > 0.05). The CC+GTR, GTR, and CC treatments exhibited significantly greater improvements compared to GFS (P < 0.05). Gingival recession increased significantly compared to presurgery for GTR, CC, and GFS treatments (-0.9 ± 1.2, -0.7 ± 0.7, and -1.2 ± 1.4 mm, respectively; P < 0.01). The results suggest that the concurrent use of a porous resorbable CC implant and GTR has limited adjunctive effect in the treatment of intrabony periodontal defects.

Original languageEnglish (US)
Pages (from-to)1301-1306
Number of pages6
JournalJournal of periodontology
Volume67
Issue number12
DOIs
StatePublished - Dec 1996

Keywords

  • Calcium carbonate/therapeutic use
  • Dental implants
  • Guided tissue regeneration
  • Periodontal pockets, therapy
  • Periodontal pockets/surgery
  • Surgical flaps

ASJC Scopus subject areas

  • Periodontics

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