Abstract
The results in the article by Zhou et al. (2020) demonstrate that the antidiabetic drug phenformin inhibits skin tumor growth and promotes keratinocyte differentiation, and an underlying mechanism is also defined. In this commentary, additional potential mechanisms through which phenformin may exert its antitumorigenic effect are described. Thus, the proposed repurposing of phenformin to treat skin cancer has merit.
Original language | English (US) |
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Pages (from-to) | 11-14 |
Number of pages | 4 |
Journal | Journal of Investigative Dermatology |
Volume | 141 |
Issue number | 1 |
DOIs |
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State | Published - Jan 2021 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Dermatology
- Cell Biology