Pleomorphic rhabdomyosarcoma presenting as a hypopharyngeal mass

Ryan A. Crane, Christopher M. Johnson, Guerard P. Grice, David P. Mullin, Kevin K. Bach

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Background Rhabdomyosarcoma (RMS) is a rare malignancy derived from skeletal muscle with approximately 40% of cases involving the head and neck. The pleomorphic variant, however, most commonly occurs in the extremities and has never, to our knowledge, been described in the pharynx. Methods A 46-year-old man with no significant medical history presented to the emergency department complaining of hemoptysis. A CT scan of the head and neck revealed a hypopharyngeal mass originally favored to be a benign process. Results Operative endoscopy revealed a previously unseen mucosal ulceration, and subsequent biopsy resulted in the final diagnosis of pleomorphic RMS. Conclusion Although quite rare, RMS should be considered in the differential diagnosis of a hypopharyngeal mass. This articleis a U.S. Government work and is in the public domain in the USA.

Original languageEnglish (US)
Pages (from-to)E85-E87
JournalHead and Neck
Issue number7
StatePublished - Jul 1 2015
Externally publishedYes


  • head and neck cancer
  • hypopharynx
  • malignancy
  • rhabdomyosarcoma
  • staging

ASJC Scopus subject areas

  • Otorhinolaryngology


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