Polycystic ovaries and ovarian hyperstimulation syndrome: A systematic review

Ian Tummon, Larisa Gavrilova-Jordan, Michael C. Allemand, Donna Session

Research output: Contribution to journalArticlepeer-review

84 Scopus citations


Objectives. To assess and quantify the relationship between polycystic ovaries (PCOs) and ovarian hyperstimulation syndrome (OHSS). Data Sources. Published studies, any language, identified through MEDLINE, EMBASE, BIOSIS, Web of Science, and bibliographies. Studies were selected if exposure (ultrasound findings of PCO before treatment) and outcome (OHSS) could be abstracted to two-by-two tables. Results. Ten studies, meeting inclusion and exclusion criteria, were analyzed. When PCO were present, the combined odds ratio for OHSS was 6.8 (95% confidence interval 4.9-9.6). Conclusion. There is a significant and consistent relationship between PCO and OHSS. When PCO are present before treatment with assisted reproduction, deliberate policies to moderate treatment appear justified.

Original languageEnglish (US)
Pages (from-to)611-616
Number of pages6
JournalActa Obstetricia et Gynecologica Scandinavica
Issue number7
StatePublished - Jul 2005
Externally publishedYes


  • Ovarian hyperstimulation syndrome
  • Polycystic ovaries
  • Systematic review
  • Ultrasonography

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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