Radium in Wisconsin Drinking Water: An Analysis of Osteosarcoma Risk

Clare E. Guse; Anne M. Marbella; Varghese George; Peter M. Layde

doi:10.1080/00039890209601412

Radium in Wisconsin Drinking Water: An Analysis of Osteosarcoma Risk

Clare E. Guse, Anne M. Marbella, Varghese George, Peter M. Layde

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio =.98; 95% confidence interval =.93,1.04; p =.56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.

Original language	English (US)
Pages (from-to)	294-303
Number of pages	10
Journal	Archives of Environmental Health
Volume	57
Issue number	4
DOIs	https://doi.org/10.1080/00039890209601412
State	Published - Jul 1 2002
Externally published	Yes

Keywords

Drinking water
Osteosarcoma
Radium

ASJC Scopus subject areas

Environmental Chemistry
General Environmental Science
Public Health, Environmental and Occupational Health
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/00039890209601412

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title = "Radium in Wisconsin Drinking Water: An Analysis of Osteosarcoma Risk",

abstract = "Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio =.98; 95% confidence interval =.93,1.04; p =.56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.",

keywords = "Drinking water, Osteosarcoma, Radium",

author = "Guse, {Clare E.} and Marbella, {Anne M.} and Varghese George and Layde, {Peter M.}",

note = "Funding Information: We would like to thank the Wisconsin Department of Natural Resources, and, in particular, Mark A. Nelson of the Bureau of Drinking Water and Groundwater, for their cooperation and assistance. This study was conducted under a contract with the Wisconsin Department of Health and Family Services, and data provided by the Wisconsin Cancer Reporting System were used. The contract final report is on file with the aforementioned Department. Financial support was provided by the Waukesha Water Utility. Submitted for publication August 1, 2000; revised; accepted for publication February 26, 2001. Requests for reprints should be sent to Clare E. Guse, MS, Department of Family and Community Medicine, 8701 Watertown Plank Road, Medical College of Wisconsin, Milwaukee, WI 53226. E-mail: cguse@mcw.edu",

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AU - Marbella, Anne M.

AU - George, Varghese

AU - Layde, Peter M.

N1 - Funding Information: We would like to thank the Wisconsin Department of Natural Resources, and, in particular, Mark A. Nelson of the Bureau of Drinking Water and Groundwater, for their cooperation and assistance. This study was conducted under a contract with the Wisconsin Department of Health and Family Services, and data provided by the Wisconsin Cancer Reporting System were used. The contract final report is on file with the aforementioned Department. Financial support was provided by the Waukesha Water Utility. Submitted for publication August 1, 2000; revised; accepted for publication February 26, 2001. Requests for reprints should be sent to Clare E. Guse, MS, Department of Family and Community Medicine, 8701 Watertown Plank Road, Medical College of Wisconsin, Milwaukee, WI 53226. E-mail: cguse@mcw.edu

PY - 2002/7/1

Y1 - 2002/7/1

N2 - Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio =.98; 95% confidence interval =.93,1.04; p =.56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.

AB - Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio =.98; 95% confidence interval =.93,1.04; p =.56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.

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Radium in Wisconsin Drinking Water: An Analysis of Osteosarcoma Risk

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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