TY - JOUR
T1 - Radium in Wisconsin Drinking Water
T2 - An Analysis of Osteosarcoma Risk
AU - Guse, Clare E.
AU - Marbella, Anne M.
AU - George, Varghese
AU - Layde, Peter M.
N1 - Funding Information:
We would like to thank the Wisconsin Department of Natural Resources, and, in particular, Mark A. Nelson of the Bureau of Drinking Water and Groundwater, for their cooperation and assistance. This study was conducted under a contract with the Wisconsin Department of Health and Family Services, and data provided by the Wisconsin Cancer Reporting System were used. The contract final report is on file with the aforementioned Department. Financial support was provided by the Waukesha Water Utility. Submitted for publication August 1, 2000; revised; accepted for publication February 26, 2001. Requests for reprints should be sent to Clare E. Guse, MS, Department of Family and Community Medicine, 8701 Watertown Plank Road, Medical College of Wisconsin, Milwaukee, WI 53226. E-mail: [email protected]
PY - 2002/7/1
Y1 - 2002/7/1
N2 - Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio =.98; 95% confidence interval =.93,1.04; p =.56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.
AB - Epidemiological studies of radium dial painters have found an association between exposure to high-dose radium and bone cancers. However, only limited data exist on the relationship between low doses of radium, as are found in some drinking water sources, and osteosarcoma. The authors conducted a population-based case-control study to examine the association between exposure to radium in drinking water and the occurrence of osteosarcoma. Estimates of radium exposure and covariates used were based on subjects' residential ZIP codes. The median radium level was not significantly associated with osteosarcoma (odds ratio =.98; 95% confidence interval =.93,1.04; p =.56). The authors found no evidence that radium, at current levels in Wisconsin drinking water, resulted in excess cases of osteosarcoma.
KW - Drinking water
KW - Osteosarcoma
KW - Radium
UR - https://www.scopus.com/pages/publications/0036664565
UR - https://www.scopus.com/pages/publications/0036664565#tab=citedBy
U2 - 10.1080/00039890209601412
DO - 10.1080/00039890209601412
M3 - Article
C2 - 12530595
AN - SCOPUS:0036664565
SN - 0003-9896
VL - 57
SP - 294
EP - 303
JO - Archives of Environmental Health
JF - Archives of Environmental Health
IS - 4
ER -
