Rapid experimental and computational determination of phenethylamine drug analogue lipophilicity

Keyphrases

• Drug Analogues 100%
• Lipophilicity 100%
• Phenethylamines 100%
• Blood-brain Barrier Permeability 50%
• Partition Coefficient 50%
• Electrospray Ionization Mass Spectrometry 50%
• Lipophilic 50%
• Computational Methods 50%
• Chloroform 50%
• Forensic Expert 50%
• Water System 50%
• Shotgun Approach 50%
• Lipinski's Rule of Five 50%
• Structural Confirmation 50%
• PAMPA-BBB 50%
• Papp 50%
• Synthetic Phenethylamines 50%
• Log P Value 50%
• Parallel Artificial Membrane Permeability Assay (PAMPA) 50%
• Apparent Permeability 50%
• Water Evaluation 50%

Biochemistry, Genetics and Molecular Biology

• Phenethylamine 100%
• Blood Brain Barrier 100%
• Lipophilicity 100%
• Partition Coefficient 50%
• Artificial Membrane 50%
• Membrane Permeability 50%
• Electrospray Mass Spectrometry 50%
• Chloroform 50%
• Apparent Permeability 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Phenethylamine 100%
• Drug Analog 100%
• Lipophilicity 100%
• Parallel Artificial Membrane Permeability Assay 100%
• Chloroform 50%
• Electrospray Ionization 50%
• Lipinski's Rule of Five 50%