Recombinant activated factor VII as an adjunct to packing for liver injury with hepatic venous disruption

Joachim Chino; David Paolini; Anh Tran; Prasad Mathew; Thomas R. Howdieshell

Recombinant activated factor VII as an adjunct to packing for liver injury with hepatic venous disruption

Joachim Chino, David Paolini, Anh Tran, Prasad Mathew, Thomas R. Howdieshell

Research output: Contribution to journal › Article › peer-review

Abstract

Injuries to the juxtahepatic veins represent a small proportion of all liver injuries but constitute the most challenging and deadly form of hepatic trauma. Recombinant activated factor VII, established as a crucial therapy for enhancing hemostasis in hemophiliacs with inhibitors, has also been used to correct coagulopathy after traumatic injury. We report two children with hepatic venous injury requiring perihepatic packing and recombinant activated factor VII to successfully control hemorrhage.

Original language	English (US)
Pages (from-to)	595-597
Number of pages	3
Journal	American Surgeon
Volume	71
Issue number	7
State	Published - Dec 1 2005
Externally published	Yes

ASJC Scopus subject areas

Surgery

Cite this

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AU - Tran, Anh

AU - Mathew, Prasad

AU - Howdieshell, Thomas R.

PY - 2005/12/1

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N2 - Injuries to the juxtahepatic veins represent a small proportion of all liver injuries but constitute the most challenging and deadly form of hepatic trauma. Recombinant activated factor VII, established as a crucial therapy for enhancing hemostasis in hemophiliacs with inhibitors, has also been used to correct coagulopathy after traumatic injury. We report two children with hepatic venous injury requiring perihepatic packing and recombinant activated factor VII to successfully control hemorrhage.

AB - Injuries to the juxtahepatic veins represent a small proportion of all liver injuries but constitute the most challenging and deadly form of hepatic trauma. Recombinant activated factor VII, established as a crucial therapy for enhancing hemostasis in hemophiliacs with inhibitors, has also been used to correct coagulopathy after traumatic injury. We report two children with hepatic venous injury requiring perihepatic packing and recombinant activated factor VII to successfully control hemorrhage.

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Recombinant activated factor VII as an adjunct to packing for liver injury with hepatic venous disruption

Abstract

ASJC Scopus subject areas

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