Recovery of rat gastric mucosa following single fluoride dosing

R. P. Easmann; D. H. Pashley; N. L. Birdsong; R. V. Mckinney; G. M. Whitford

doi:10.1111/j.1600-0714.1985.tb00468.x

Recovery of rat gastric mucosa following single fluoride dosing

R. P. Easmann, D. H. Pashley, N. L. Birdsong, R. V. Mckinney, G. M. Whitford

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Rats' stomachs were intubated with 0.1 N HCl or 100 mM NaF in 0.1 N HCl and excised after 1, 12, 24, 48 h or 7 days for light microscopy. The NaF solution caused erosive injury to the oxyntic glandular mucosa 1 h after application. Progressive stages of recovery were seen at 12, 24 and 48 h after fluoride dosing. Complete recovery was seen 7 days after exposure to fluoride. The kinetics of the recovery process from fluoride injury appear to he similar to those which have been reported for gastric injury produced by other substances.

Original language	English (US)
Pages (from-to)	779-792
Number of pages	14
Journal	Journal of Oral Pathology & Medicine
Volume	14
Issue number	10
DOIs	https://doi.org/10.1111/j.1600-0714.1985.tb00468.x
State	Published - Nov 1985
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine
Oral Surgery
Otorhinolaryngology
Cancer Research
Periodontics

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1600-0714.1985.tb00468.x

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title = "Recovery of rat gastric mucosa following single fluoride dosing",

abstract = "Rats' stomachs were intubated with 0.1 N HCl or 100 mM NaF in 0.1 N HCl and excised after 1, 12, 24, 48 h or 7 days for light microscopy. The NaF solution caused erosive injury to the oxyntic glandular mucosa 1 h after application. Progressive stages of recovery were seen at 12, 24 and 48 h after fluoride dosing. Complete recovery was seen 7 days after exposure to fluoride. The kinetics of the recovery process from fluoride injury appear to he similar to those which have been reported for gastric injury produced by other substances.",

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year = "1985",

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doi = "10.1111/j.1600-0714.1985.tb00468.x",

language = "English (US)",

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AU - Easmann, R. P.

AU - Pashley, D. H.

AU - Birdsong, N. L.

AU - Mckinney, R. V.

AU - Whitford, G. M.

PY - 1985/11

Y1 - 1985/11

N2 - Rats' stomachs were intubated with 0.1 N HCl or 100 mM NaF in 0.1 N HCl and excised after 1, 12, 24, 48 h or 7 days for light microscopy. The NaF solution caused erosive injury to the oxyntic glandular mucosa 1 h after application. Progressive stages of recovery were seen at 12, 24 and 48 h after fluoride dosing. Complete recovery was seen 7 days after exposure to fluoride. The kinetics of the recovery process from fluoride injury appear to he similar to those which have been reported for gastric injury produced by other substances.

AB - Rats' stomachs were intubated with 0.1 N HCl or 100 mM NaF in 0.1 N HCl and excised after 1, 12, 24, 48 h or 7 days for light microscopy. The NaF solution caused erosive injury to the oxyntic glandular mucosa 1 h after application. Progressive stages of recovery were seen at 12, 24 and 48 h after fluoride dosing. Complete recovery was seen 7 days after exposure to fluoride. The kinetics of the recovery process from fluoride injury appear to he similar to those which have been reported for gastric injury produced by other substances.

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JO - Journal of Oral Pathology & Medicine

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ER -

Recovery of rat gastric mucosa following single fluoride dosing

Abstract

ASJC Scopus subject areas

UN SDGs

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