Abstract
Erectile dysfunction is a common entity in clinical practice. Primary erectile dysfunction, not related to vasculopathy or psychiatric disorder, can be readily treated with phosphodiesterase inhibitors. These drugs have many physiologic effects that can alter a patient's hemodynamic profile considerably, especially in the presence of concomitant structural heart disease, specifically valvular heart disease. Although some contraindications to the use of PDE5 inhibitors in patients with cardiovascular disease are defined, the effect of these drugs in the presence of valvular heart disease is not well documented. The purpose of this review is to analyze the data regarding the safety of PDE5 inhibitors in patients with valvular heart disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 372-376 |
| Number of pages | 5 |
| Journal | Journal of Cardiovascular Pharmacology |
| Volume | 78 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 3 2021 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Valvular heart disease
- pharmacologic safety
- phosphodiesterase inhibitors
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Pharmacology
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