Scan findings of various myocardial spect agents in a case of amyloid polyneuropathy with suspected myocardial involvement

Ali Syed Arbab; Kiyoshi Koizumi; Keiji Toyama; Takao Arai; Tatsuya Yoshitomi; Tsutomu Araki

doi:10.1007/BF03164822

Scan findings of various myocardial spect agents in a case of amyloid polyneuropathy with suspected myocardial involvement

Ali Syed Arbab, Kiyoshi Koizumi, Keiji Toyama, Takao Arai, Tatsuya Yoshitomi, Tsutomu Araki

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A 31-year-old male having familial amyloid polyneuropathy underwent a Tc-99m(V)-DMSA study to evaluate the myocardial involvement. The patient also underwent Tl-201, I-123-BMIPP and I-123-MIBG myocardial SPECT studies to evaluate blood perfusion, fatty acid metabolism and sympathetic function of the heart, respectively. Tc-99m(V)-DMSA SPECT showed uptake to the myocardium indicating myocardial involvement of amyloidosis. Both Tl-201 and I-123- BMIPP studies showed normal uptake indicating normal blood perfusion and fatty acid metabolism but I-123-MIBG SPECT showed no uptake to the heart, indicating severe impairment of sympathetic function.

Original language	English (US)
Pages (from-to)	139-141
Number of pages	3
Journal	Annals of Nuclear Medicine
Volume	11
Issue number	2
DOIs	https://doi.org/10.1007/BF03164822
State	Published - May 1997
Externally published	Yes

Keywords

Amyloidosis
I-123-BMIPP
I-123-MIBG
Tc-99m(V)-DMSA
Tl-201

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1007/BF03164822

Cite this

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title = "Scan findings of various myocardial spect agents in a case of amyloid polyneuropathy with suspected myocardial involvement",

abstract = "A 31-year-old male having familial amyloid polyneuropathy underwent a Tc-99m(V)-DMSA study to evaluate the myocardial involvement. The patient also underwent Tl-201, I-123-BMIPP and I-123-MIBG myocardial SPECT studies to evaluate blood perfusion, fatty acid metabolism and sympathetic function of the heart, respectively. Tc-99m(V)-DMSA SPECT showed uptake to the myocardium indicating myocardial involvement of amyloidosis. Both Tl-201 and I-123- BMIPP studies showed normal uptake indicating normal blood perfusion and fatty acid metabolism but I-123-MIBG SPECT showed no uptake to the heart, indicating severe impairment of sympathetic function.",

keywords = "Amyloidosis, I-123-BMIPP, I-123-MIBG, Tc-99m(V)-DMSA, Tl-201",

author = "Arbab, {Ali Syed} and Kiyoshi Koizumi and Keiji Toyama and Takao Arai and Tatsuya Yoshitomi and Tsutomu Araki",

year = "1997",

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doi = "10.1007/BF03164822",

language = "English (US)",

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TY - JOUR

T1 - Scan findings of various myocardial spect agents in a case of amyloid polyneuropathy with suspected myocardial involvement

AU - Arbab, Ali Syed

AU - Koizumi, Kiyoshi

AU - Toyama, Keiji

AU - Arai, Takao

AU - Yoshitomi, Tatsuya

AU - Araki, Tsutomu

PY - 1997/5

Y1 - 1997/5

N2 - A 31-year-old male having familial amyloid polyneuropathy underwent a Tc-99m(V)-DMSA study to evaluate the myocardial involvement. The patient also underwent Tl-201, I-123-BMIPP and I-123-MIBG myocardial SPECT studies to evaluate blood perfusion, fatty acid metabolism and sympathetic function of the heart, respectively. Tc-99m(V)-DMSA SPECT showed uptake to the myocardium indicating myocardial involvement of amyloidosis. Both Tl-201 and I-123- BMIPP studies showed normal uptake indicating normal blood perfusion and fatty acid metabolism but I-123-MIBG SPECT showed no uptake to the heart, indicating severe impairment of sympathetic function.

AB - A 31-year-old male having familial amyloid polyneuropathy underwent a Tc-99m(V)-DMSA study to evaluate the myocardial involvement. The patient also underwent Tl-201, I-123-BMIPP and I-123-MIBG myocardial SPECT studies to evaluate blood perfusion, fatty acid metabolism and sympathetic function of the heart, respectively. Tc-99m(V)-DMSA SPECT showed uptake to the myocardium indicating myocardial involvement of amyloidosis. Both Tl-201 and I-123- BMIPP studies showed normal uptake indicating normal blood perfusion and fatty acid metabolism but I-123-MIBG SPECT showed no uptake to the heart, indicating severe impairment of sympathetic function.

KW - Amyloidosis

KW - I-123-BMIPP

KW - I-123-MIBG

KW - Tc-99m(V)-DMSA

KW - Tl-201

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DO - 10.1007/BF03164822

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JO - Annals of Nuclear Medicine

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IS - 2

ER -

Scan findings of various myocardial spect agents in a case of amyloid polyneuropathy with suspected myocardial involvement

Abstract

Keywords

ASJC Scopus subject areas

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