Screening of seven putative 45,X subjects with deoxyribonucleic acid probes to detect low-level mosaicism for Y cell lines

Sandra P.T. Tho; Ali Behzadian; Paul G. McDonough

doi:10.1016/0002-9378(90)90820-W

Screening of seven putative 45,X subjects with deoxyribonucleic acid probes to detect low-level mosaicism for Y cell lines

Sandra P.T. Tho, Ali Behzadian, Paul G. McDonough

Physiology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The frequency of monosomy X in cytogenetically abnormal abortion material (10% to 15%) suggests that viable 45,X subjects might have covert mosaicism for X or Y cell lines. The deoxyribonucleic acid samples from seven 45,X subjects with Tumer syndrome were examined with three Y-specific deoxyribonucleic acid probes. Successive hybridizations with each of these three sensitive deoxyribonucleic acid probes did not reveal any Y-specific band.

Original language	English (US)
Pages (from-to)	59-60
Number of pages	2
Journal	American journal of obstetrics and gynecology
Volume	162
Issue number	1
DOIs	https://doi.org/10.1016/0002-9378(90)90820-W
State	Published - Jan 1990

Keywords

45,X
4B2
Y deoxyribonucleic probes
Y97
pS4

ASJC Scopus subject areas

Obstetrics and Gynecology

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10.1016/0002-9378(90)90820-W

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abstract = "The frequency of monosomy X in cytogenetically abnormal abortion material (10% to 15%) suggests that viable 45,X subjects might have covert mosaicism for X or Y cell lines. The deoxyribonucleic acid samples from seven 45,X subjects with Tumer syndrome were examined with three Y-specific deoxyribonucleic acid probes. Successive hybridizations with each of these three sensitive deoxyribonucleic acid probes did not reveal any Y-specific band.",

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AU - Behzadian, Ali

AU - McDonough, Paul G.

PY - 1990/1

Y1 - 1990/1

N2 - The frequency of monosomy X in cytogenetically abnormal abortion material (10% to 15%) suggests that viable 45,X subjects might have covert mosaicism for X or Y cell lines. The deoxyribonucleic acid samples from seven 45,X subjects with Tumer syndrome were examined with three Y-specific deoxyribonucleic acid probes. Successive hybridizations with each of these three sensitive deoxyribonucleic acid probes did not reveal any Y-specific band.

AB - The frequency of monosomy X in cytogenetically abnormal abortion material (10% to 15%) suggests that viable 45,X subjects might have covert mosaicism for X or Y cell lines. The deoxyribonucleic acid samples from seven 45,X subjects with Tumer syndrome were examined with three Y-specific deoxyribonucleic acid probes. Successive hybridizations with each of these three sensitive deoxyribonucleic acid probes did not reveal any Y-specific band.

KW - 45,X

KW - 4B2

KW - Y deoxyribonucleic probes

KW - Y97

KW - pS4

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Screening of seven putative 45,X subjects with deoxyribonucleic acid probes to detect low-level mosaicism for Y cell lines

Abstract

Keywords

ASJC Scopus subject areas

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