Sequential assessment of troponin in the diagnosis of myocardial infarction.

Brandon Edwards, Irsha Washington, Lester Pretlow, Gregory Passmore, James Dias, Scott Wise

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


According to the American Heart Association, cardiovascular disease accounts for more than one third of all deaths in the United States. 1 The purpose of this retrospective case-control study was to determine which sample taken in a sequential draw was most important in diagnosing an acute myocardial infarction (AMI). One-hundred subjects were selected from a convenience sample. The "risk" of AMI diagnosis was modeled using binary multiple logistic regression. Overall, 78% (39 out of 50 cases) were diagnosed with an AMI at Tinitiai. Clearly, the initial cTnI assay is the most critical of the four sequential time points for the accurate assessment of the presence or absence of an AMI. Most importantly, sequential troponin testing increased the ability to diagnose AMI by 10-fold.

Original languageEnglish (US)
Pages (from-to)95-99
Number of pages5
JournalUnknown Journal
Issue number2
StatePublished - 2013
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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