TY - JOUR
T1 - Severe late-onset ovarian hyperstimulation syndrome presenting with liver dysfunction after in vitro fertilization
T2 - A case report
AU - Chae-Kim, Jennifer J.
AU - Roman, Robert
AU - Hawkins, Kristina
AU - Gavrilova-Jordan, Larisa
N1 - Publisher Copyright:
© 2021
PY - 2021/7
Y1 - 2021/7
N2 - Ovarian hyperstimulation syndrome (OHSS) is a feared complication of controlled ovarian stimulation (COS) and can be associated with significant morbidity and mortality. Risk factors for OHSS include a history of OHSS, young age, low body mass index (BMI), polycystic ovary syndrome, elevated serum levels of anti-Müllerian hormone (AMH), large number of recruited follicles, elevated serum levels of estradiol, and higher gonadotropin doses during COS. However, OHSS may develop in patients with minimal risk factors. We present the case of a patient with minimal risk factors who developed severe late-onset OHSS in early pregnancy with liver dysfunction requiring hospitalization. After hospital discharge, her pregnancy resulted in a term live birth. We recommend that clinicians include OHSS in the differential diagnosis of elevated levels of liver enzymes in early pregnancy.
AB - Ovarian hyperstimulation syndrome (OHSS) is a feared complication of controlled ovarian stimulation (COS) and can be associated with significant morbidity and mortality. Risk factors for OHSS include a history of OHSS, young age, low body mass index (BMI), polycystic ovary syndrome, elevated serum levels of anti-Müllerian hormone (AMH), large number of recruited follicles, elevated serum levels of estradiol, and higher gonadotropin doses during COS. However, OHSS may develop in patients with minimal risk factors. We present the case of a patient with minimal risk factors who developed severe late-onset OHSS in early pregnancy with liver dysfunction requiring hospitalization. After hospital discharge, her pregnancy resulted in a term live birth. We recommend that clinicians include OHSS in the differential diagnosis of elevated levels of liver enzymes in early pregnancy.
KW - Case report
KW - Early pregnancy
KW - Liver dysfunction
KW - Ovarian hyperstimulation syndrome
KW - Transaminitis
UR - http://www.scopus.com/inward/record.url?scp=85107617879&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85107617879&partnerID=8YFLogxK
U2 - 10.1016/j.crwh.2021.e00332
DO - 10.1016/j.crwh.2021.e00332
M3 - Article
AN - SCOPUS:85107617879
SN - 2214-9112
VL - 31
JO - Case Reports in Women's Health
JF - Case Reports in Women's Health
M1 - e00332
ER -