Abstract
We have characterized a novel recessive mouse mutation, named sooty foot, that increases the pigmentation of the exposed skin on the foot pads, the genital region, around the snout and muzzle, the ears, and the tail. By contrast, the pigmentation of the hair is unaffected. We have localized the mutation to Chromosome 2 by polymerase chain reaction (PCR) amplification of simple sequence repeats from pooled DNA from backcross progeny. In an extended backcross we have generated a detailed map of the region around sooty foot.
Original language | English (US) |
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Pages (from-to) | 631-635 |
Number of pages | 5 |
Journal | Mammalian Genome |
Volume | 8 |
Issue number | 9 |
DOIs | |
State | Published - Sep 1997 |
ASJC Scopus subject areas
- Genetics