Stem cell therapy for neonatal hypoxic-ischemic brain injury

James Carroll

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Various varieties of stem cells and methods of their administration are proposed as therapeutic modalities for neonatal hypoxic–ischemic (HI) brain injury. The widespread use of stem cells for this purpose and others, despite the lack of strong clinical evidence for their efficacy in most clinical situations, makes it incumbent to review the pathophysiology of the clinical condition of neonatal HI brain injury, the preclinical data dealing with animal HI injury, and the available clinical studies.

Original languageEnglish (US)
Title of host publicationCell Therapy for Brain Injury
PublisherSpringer International Publishing
Pages307-320
Number of pages14
ISBN (Electronic)9783319150635
ISBN (Print)9783319150628
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine
  • General Neuroscience

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