Stenting in non-small cell lung cancer: How does it affect the outcomes?

Nagla Abdel Karim, Sinan Khaddam, Mahmoud Shehata, Ahmed Mostafa, Mohamed Magdy, Ihab Eldessouki, Changchun Xie, Sadia Benzaquen

Research output: Contribution to journalArticlepeer-review


Objective: Approximately 30% of lung cancer patients develop central airway obstruction (CAO) that remarkably shortens survival. There is little data about the benefis of stenting within this heterogeneous patient group. Our objective was to review their overall survival (OS) and their risk of hospitalization versus patients who did not have lesions requiring stent placement. Methods: We retrospectively reviewed charts of 171 non-small cell lung cancer (NSCLC) patients who underwent bronchoscopy in the University of Cincinnati Cancer Center from the year 2011 to 2013. Twenty-fie patients with advanced lung cancer were evaluated by interventional pulmonology service for endobronchial stent placement for CAO. Eight patients did not require placement of a stent and 17 had obstructive lesions that required stenting by interventional pulmonology. Results: Demographical parameters such as age and gender did not have a signifiant impact on the risk of hospitalization or OS of both groups of patients, however, those whose lesions did not mandate stent placement had signifiantly lower odds of hospitalization compared to patients with CAO requiring a stent (OR: 15.913, 95% CI: 1.211-209.068, P = 0.0352). Patients with advanced NSCLC and CAO that required stent placement had an OS of 13.9 m [3.9-19.9 m] compared to an OS of 23.9 m for patients with CAO not requiring a stent. We found out that patients with less severe CAO have lower odds of hospitalization and better OS compared to patients with CAO mandating stent placement. Conclusion: CAO patients with interventional pulmonology (IP) evaluation and management in addition, may have improved OS suggesting that IP consultation might offer both improvement in quality of life and overall survival to patients with advanced NSCLC and CAO.

Original languageEnglish (US)
Pages (from-to)175-178
Number of pages4
JournalAsian Pacific Journal of Cancer Prevention
Issue number1
StatePublished - Jan 1 2020
Externally publishedYes


  • Central airway obstruction
  • Lung cancer
  • Non-small cell lung cancer
  • Stenting

ASJC Scopus subject areas

  • Epidemiology
  • Oncology
  • Public Health, Environmental and Occupational Health
  • Cancer Research


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