Subcutaneously Implanted Alginate as a Continuous-release Source of Fluoride

Gary M. Whitford, Jan Ekstrand, Richard S. Callan, David E. Pearson

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The fluoride concentrations of seven brands of alginate ranged from 8600 to 30,500 ppm. In acute and chronic in vivo studies, fluoride was continuously released from subcutaneously implanted alginate cylinders for up to three weeks. This technique is a simple and economical method for elevating soft and hard tissue fluoride levels.

Original languageEnglish (US)
Pages (from-to)186-191
Number of pages6
JournalJournal of Dental Research
Issue number2
StatePublished - Feb 1980

ASJC Scopus subject areas

  • Dentistry(all)


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