Surface-Enhanced Raman Scattering for Label-Free Living Single Cell Analysis

Gamze Kuku, Mine Altunbek, Mustafa Culha

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


Single cell analysis is an active research area with the hope that cellular process can be deciphered from a single living cell other than a cell population. Surface enhanced Raman scattering (SERS) has been increasingly investigated for single cell analysis with its ability to provide information about real-time dynamics of molecular processes taking place in living cells, especially upon external stimulation, in a contactless, noninvasive, and nondestructive way. In this perspective, the fundamental concepts of single cell-SERS analysis including origin of spectral bands and experimental parameters for spectral reproducibility are summarized along with the recent developments.

Original languageEnglish (US)
Pages (from-to)11160-11166
Number of pages7
JournalAnalytical Chemistry
Issue number21
StatePublished - Nov 7 2017
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry

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