Surgery in Bone Sarcoma: Allograft vs. Megaprosthesis

Limb reconstruction following bone tumor resection is challenging and includes a variety of options. The most common options include endoprostheses, allograft prosthetic composites, and osteoarticular allografts. Although any anatomic location may be subject to reconstruction, some evoke more controversy than others. Currently, the most disputed sites of reconstruction are the proximal humerus and proximal tibia. The debate centers on a balance between durability (endoprosthesis) and function (allograft prosthetic composites and osteoarticular allografts). Each method has its pros and cons which must be weighed along with patient factors when deciding which to use.