Surgical management of epilepsy

J. R. Smith, H. F. Flanigin, D. W. King, B. B. Gallagher, D. W. Loring, K. J. Meador, A. M. Murro, G. P. Lee

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


About 300,000 people in the United States suffer from medically uncontrolled focal epilepsy. It is estimated that about 40,000 of these patients are candidates for surgery. Underuse of surgical treatment of epilepsy is reflected by the fact that only about 1% of these candidates are operated on. Candidates for ablative surgery (ie, removal of seizure focus) must have a focus demonstrated by either extracranial or intracranial electrode recordings. Nearly half of the patients whoe have ablative surgery become seizure-free, and nearly two thirds have no seizures or only rare ones. Candidates for corpus callosotomy are those patients with multiple seizure types and nonfocal EEG abnormalities. Almost half of these patients have at least a 50% reduction in seizure frequency. Patients with infantile hemiplegia and seizures may have marked improvement in seizure control after physiologic hemispherectomy.

Original languageEnglish (US)
Pages (from-to)736-742
Number of pages7
JournalSouthern medical journal
Issue number6
StatePublished - 1989

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Surgical management of epilepsy'. Together they form a unique fingerprint.

Cite this