Surgical management of intractable epilepsy in children with hemophilia

David John Yeh; Mark Lee; Yong D Park; Joseph R. Smith; Alton L. Lightsey

doi:10.1159/000029761

Surgical management of intractable epilepsy in children with hemophilia

David John Yeh, Mark Lee, Yong D Park, Joseph R. Smith, Alton L. Lightsey

Child Neurology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Intracranial hemorrhage occurs in 2-8% of patients with hemophilia and can result in neurologic sequelae including seizure disorders. There is a paucity of data concerning the surgical treatment of epilepsy in children with hemophilia. We review our experience with 2 children who developed medically refractory seizure disorders. Both children underwent hemispherotomy, at 18 months (case 1) and 13 years of age (case 2), respectively. Perioperative management included continuous factor replacement. Both children tolerated surgical intervention without complications or increased neurologic deficit. Case 2 showed a 90% reduction in seizure frequency, and case 1 is seizure free. Surgical management of intractable epilepsy in children with hemophilia is safe and effective. Copyright (C) 2000 S. Karger AG, Basel.

Original language	English (US)
Pages (from-to)	88-94
Number of pages	7
Journal	Stereotactic and Functional Neurosurgery
Volume	73
Issue number	1-4
DOIs	https://doi.org/10.1159/000029761
State	Published - Jan 1 1999

Keywords

Epilepsy
Epilepsy surgery
Hemispherotomy
Hemophilia
Intracranial hemorrhage

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.1159/000029761

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title = "Surgical management of intractable epilepsy in children with hemophilia",

abstract = "Intracranial hemorrhage occurs in 2-8% of patients with hemophilia and can result in neurologic sequelae including seizure disorders. There is a paucity of data concerning the surgical treatment of epilepsy in children with hemophilia. We review our experience with 2 children who developed medically refractory seizure disorders. Both children underwent hemispherotomy, at 18 months (case 1) and 13 years of age (case 2), respectively. Perioperative management included continuous factor replacement. Both children tolerated surgical intervention without complications or increased neurologic deficit. Case 2 showed a 90% reduction in seizure frequency, and case 1 is seizure free. Surgical management of intractable epilepsy in children with hemophilia is safe and effective. Copyright (C) 2000 S. Karger AG, Basel.",

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AU - Yeh, David John

AU - Lee, Mark

AU - Park, Yong D

AU - Smith, Joseph R.

AU - Lightsey, Alton L.

PY - 1999/1/1

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N2 - Intracranial hemorrhage occurs in 2-8% of patients with hemophilia and can result in neurologic sequelae including seizure disorders. There is a paucity of data concerning the surgical treatment of epilepsy in children with hemophilia. We review our experience with 2 children who developed medically refractory seizure disorders. Both children underwent hemispherotomy, at 18 months (case 1) and 13 years of age (case 2), respectively. Perioperative management included continuous factor replacement. Both children tolerated surgical intervention without complications or increased neurologic deficit. Case 2 showed a 90% reduction in seizure frequency, and case 1 is seizure free. Surgical management of intractable epilepsy in children with hemophilia is safe and effective. Copyright (C) 2000 S. Karger AG, Basel.

AB - Intracranial hemorrhage occurs in 2-8% of patients with hemophilia and can result in neurologic sequelae including seizure disorders. There is a paucity of data concerning the surgical treatment of epilepsy in children with hemophilia. We review our experience with 2 children who developed medically refractory seizure disorders. Both children underwent hemispherotomy, at 18 months (case 1) and 13 years of age (case 2), respectively. Perioperative management included continuous factor replacement. Both children tolerated surgical intervention without complications or increased neurologic deficit. Case 2 showed a 90% reduction in seizure frequency, and case 1 is seizure free. Surgical management of intractable epilepsy in children with hemophilia is safe and effective. Copyright (C) 2000 S. Karger AG, Basel.

KW - Epilepsy

KW - Epilepsy surgery

KW - Hemispherotomy

KW - Hemophilia

KW - Intracranial hemorrhage

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Surgical management of intractable epilepsy in children with hemophilia

Abstract

Keywords

ASJC Scopus subject areas

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