Surgical Management of Perineural Spread of Head and Neck Cancers

C. Arturo Solares, Eric Mason, Benedict J. Panizza

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The surgical management of perineural spread of head and neck cancers has become an integral part in the contemporary treatment of this pathology. We now understand that tumour spreads within the epineurium and in a continuous fashion. We also can rely on the accuracy of magnetic resonance neurography in detecting and defining the extent of disease. With modern skull base techniques and a greater understanding of the anatomy in this region, specific operations can be designed to help eradicate disease. We review the current approaches and techniques used that enable us to better obtain tumour free margins and hence improve survival.

Original languageEnglish (US)
Pages (from-to)140-149
Number of pages10
JournalJournal of Neurological Surgery, Part B: Skull Base
Issue number2
StatePublished - Mar 18 2016


  • head and neck
  • perineural invasion
  • perineural spread
  • skin cancer
  • skull base surgery
  • squamous cell carcinoma

ASJC Scopus subject areas

  • Clinical Neurology


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