TY - JOUR
T1 - Synthesis, Functionalization, and Bioapplications of Two-Dimensional Boron Nitride Nanomaterials
AU - Emanet, Melis
AU - Sen, Özlem
AU - Taşkin, Irem Çulha
AU - Çulha, Mustafa
N1 - Funding Information:
The authors acknowledge the support they received from Yeditepe University.
Publisher Copyright:
© Copyright © 2019 Emanet, Sen, Taşkin and Çulha.
PY - 2019/12/10
Y1 - 2019/12/10
N2 - Two-dimensional boron nitride nanostructures (2D-BNNs) have been increasingly investigated for their applications in several scientific and technological areas. This considerable interest is due to their unique physicochemical properties, which include high hydrophobicity, heat and electrical insulation, resistance to oxidation, antioxidation capacity, thermal conductivity, high chemical stability, mechanical strength, and hydrogen storage capacity. They are also used as fillers, antibacterial agents, protective coating agents, lubricants, boron neutron capture therapy agents, nanocarriers for drug delivery, and for the receptor phase in chemosensors. The investigations for their use in medicine and biomedicine are very promising, including cancer therapy and wound healing. In this review, 2D-BNNs synthesis and their surface modification strategies, biocompatibility, and bioapplication studies are discussed. Finally, a perspective for the future use of these novel nanomaterials in the biomedical field is provided.
AB - Two-dimensional boron nitride nanostructures (2D-BNNs) have been increasingly investigated for their applications in several scientific and technological areas. This considerable interest is due to their unique physicochemical properties, which include high hydrophobicity, heat and electrical insulation, resistance to oxidation, antioxidation capacity, thermal conductivity, high chemical stability, mechanical strength, and hydrogen storage capacity. They are also used as fillers, antibacterial agents, protective coating agents, lubricants, boron neutron capture therapy agents, nanocarriers for drug delivery, and for the receptor phase in chemosensors. The investigations for their use in medicine and biomedicine are very promising, including cancer therapy and wound healing. In this review, 2D-BNNs synthesis and their surface modification strategies, biocompatibility, and bioapplication studies are discussed. Finally, a perspective for the future use of these novel nanomaterials in the biomedical field is provided.
KW - bioapplication
KW - biocompatibility
KW - functionalization
KW - synthesis
KW - two-dimensional boron nitride nanoparticles
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U2 - 10.3389/fbioe.2019.00363
DO - 10.3389/fbioe.2019.00363
M3 - Review article
AN - SCOPUS:85077250143
SN - 2296-4185
VL - 7
JO - Frontiers in Bioengineering and Biotechnology
JF - Frontiers in Bioengineering and Biotechnology
M1 - 363
ER -