Synthesis, Functionalization, and Bioapplications of Two-Dimensional Boron Nitride Nanomaterials

Melis Emanet, Özlem Sen, Irem Çulha Taşkin, Mustafa Çulha

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations


Two-dimensional boron nitride nanostructures (2D-BNNs) have been increasingly investigated for their applications in several scientific and technological areas. This considerable interest is due to their unique physicochemical properties, which include high hydrophobicity, heat and electrical insulation, resistance to oxidation, antioxidation capacity, thermal conductivity, high chemical stability, mechanical strength, and hydrogen storage capacity. They are also used as fillers, antibacterial agents, protective coating agents, lubricants, boron neutron capture therapy agents, nanocarriers for drug delivery, and for the receptor phase in chemosensors. The investigations for their use in medicine and biomedicine are very promising, including cancer therapy and wound healing. In this review, 2D-BNNs synthesis and their surface modification strategies, biocompatibility, and bioapplication studies are discussed. Finally, a perspective for the future use of these novel nanomaterials in the biomedical field is provided.

Original languageEnglish (US)
Article number363
JournalFrontiers in Bioengineering and Biotechnology
StatePublished - Dec 10 2019
Externally publishedYes


  • bioapplication
  • biocompatibility
  • functionalization
  • synthesis
  • two-dimensional boron nitride nanoparticles

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Histology
  • Biomedical Engineering


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