@inbook{d1a45fb3e62349b399ce0376f6d465a8,
title = "Targeting ros-mediated crosstalk between autophagy and apoptosis in cancer",
abstract = "The control of crosstalk between autophagy and apoptosis in tumor cells can remove a critical barrier to comprehensive and efficacious treatment for cancer. Reactive oxygen species (ROS), by-products of redox homeostasis, are critical for regulating the balance between autophagy and apoptosis in cancer cells upon different drug treatments and gene modifications. The mechanisms and consequences involved in ROS-mediated crosstalk between apoptosis and autophagy are extremely complex in cancer cells. Here, we mainly discuss the closely linked relationship between ROS levels, autophagy, and apoptosis in cancer therapy.",
keywords = "Anticancer strategy, Apoptosis, Autophagy, Cancer, ROS, Reactive oxygen species",
author = "Lixia Gao and Jenni Loveless and Chloe Shay and Yong Teng",
note = "Publisher Copyright: {\textcopyright} Springer Nature Switzerland AG 2020.",
year = "2020",
doi = "10.1007/978-3-030-42667-5_1",
language = "English (US)",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer",
pages = "1--12",
booktitle = "Advances in Experimental Medicine and Biology",
}