TY - JOUR
T1 - The Association of Intraocular Pressure with Obesity and Cardiometabolic Risk in a Young Farmworker Population
AU - Reddy, Aditya
AU - Halenda, Kevin
AU - Cromer, Pamela
AU - Chen, Li
AU - Butler, Julian
AU - Raed, Anas
AU - Bhagatwala, Jigar
AU - Sponseller, Tracie
AU - Bollinger, Kathryn
AU - Zhu, Haidong
AU - Young, Lufei
AU - Layman, Debbie
AU - Dong, Yanbin
N1 - Funding Information:
Received for publication May 12, 2020; accepted September 7, 2020. From the *Department of Medicine, Georgia Prevention Institute, Medical College of Georgia; §Department of Medicine, Medical College of Georgia; †Department of Ophthalmology, Medical College of Georgia; ‡College of Nursing, Augusta University; and ∥Community Liaison between Augusta University and Costa-Lay-man Farm, Augusta, GA. A.R. and K.H.: denotes cofirst authorship. Supported in part by Community Partnership Study Award to D.L. and Y.D. from Institute of Preventative and Public Health at Augusta University. Disclosure: The authors declare no conflict of interest. Reprints: Yanbin Dong, MD, PhD, Department of Medicine, Georgia Prevention Institute, Medical College of Georgia, Augusta University, 1499 Walton Way, HS-1755, Augusta, GA 30901 (e-mail: ydong@augusta.edu). Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved. DOI: 10.1097/IJG.0000000000001673
PY - 2021/1
Y1 - 2021/1
N2 - Précis:Intraocular pressure (IOP) was found to be significantly correlated with body mass index (BMI), waist circumference, and diastolic blood pressure (DBP) in a farmworker population located in the southeast Georgia, USA. BMI was correlated with IOP, independent of systemic blood pressures.Purpose:Elevated IOP is a known risk factor for glaucomatous optic neuropathy and is believed to be associated with obesity and cardiometabolic diseases. The high prevalence of these conditions in the United States necessitates an evaluation of the relationship among obesity, cardiometabolic risks, and IOP among understudied younger populations.Materials and Methods:Farmworker data were collected from the annual Costa-Layman Health Fair between 2013 and 2017. Correlations of IOP with demographic factors, obesity, and cardiometabolic risks were analyzed using analysis of covariance, partial Pearson correlations, and linear regressions.Results:In the farmworker population (n=346), the mean IOP was 15.5 mm Hg and the prevalence of ocular hypertension (IOP>21 mm Hg) was 5.5%. BMI, waist circumference, and DBP were significantly correlated (r=0.192, P=0.001; r=0.128, P=0.017; r=0.142, P=0.007, respectively) with IOP when adjusted for age, sex, and ethnicity. Each 10 mm Hg increase in DBP corresponded with a 0.51 mm Hg increase in IOP. With adjustment for age, sex, ethnicity, systolic blood pressure, and DBP, BMI remained significantly correlated with IOP (r=0.166, P=0.002).Conclusions:Higher IOP is associated with obesity measures including BMI and waist circumference and is correlated with DBP. These findings suggest that BMI is an independent risk factor for elevated IOP.
AB - Précis:Intraocular pressure (IOP) was found to be significantly correlated with body mass index (BMI), waist circumference, and diastolic blood pressure (DBP) in a farmworker population located in the southeast Georgia, USA. BMI was correlated with IOP, independent of systemic blood pressures.Purpose:Elevated IOP is a known risk factor for glaucomatous optic neuropathy and is believed to be associated with obesity and cardiometabolic diseases. The high prevalence of these conditions in the United States necessitates an evaluation of the relationship among obesity, cardiometabolic risks, and IOP among understudied younger populations.Materials and Methods:Farmworker data were collected from the annual Costa-Layman Health Fair between 2013 and 2017. Correlations of IOP with demographic factors, obesity, and cardiometabolic risks were analyzed using analysis of covariance, partial Pearson correlations, and linear regressions.Results:In the farmworker population (n=346), the mean IOP was 15.5 mm Hg and the prevalence of ocular hypertension (IOP>21 mm Hg) was 5.5%. BMI, waist circumference, and DBP were significantly correlated (r=0.192, P=0.001; r=0.128, P=0.017; r=0.142, P=0.007, respectively) with IOP when adjusted for age, sex, and ethnicity. Each 10 mm Hg increase in DBP corresponded with a 0.51 mm Hg increase in IOP. With adjustment for age, sex, ethnicity, systolic blood pressure, and DBP, BMI remained significantly correlated with IOP (r=0.166, P=0.002).Conclusions:Higher IOP is associated with obesity measures including BMI and waist circumference and is correlated with DBP. These findings suggest that BMI is an independent risk factor for elevated IOP.
KW - cardiometabolic risk
KW - farmworkers
KW - intraocular pressure
KW - obesity
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U2 - 10.1097/IJG.0000000000001673
DO - 10.1097/IJG.0000000000001673
M3 - Article
C2 - 33065612
SN - 1057-0829
VL - 30
SP - 24
EP - 31
JO - Journal of Glaucoma
JF - Journal of Glaucoma
IS - 1
ER -