Abstract
We have refined the location of the Brn-3a genomic locus (POU4F1), using somatic cell hybrid analysis, to 13q21.→q22. Furthermore, we have shown that two YACs, known to contain the closest marker linked to neuronal ceroidlipofuscinosis (CLN5), also contains the Brn-3a gene. As one of these YACs is only 320 kb long, this localises POU4F1 within the critical region defining the CLN5 locus, and raises the possibility that POU4F1 is a candidate gene for CLN5.
Original language | English (US) |
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Pages (from-to) | 225-226 |
Number of pages | 2 |
Journal | Cytogenetics and Cell Genetics |
Volume | 74 |
Issue number | 3 |
DOIs | |
State | Published - Jan 1 1996 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Cell Biology