TY - JOUR
T1 - The dentine remineralization activity of a desensitizing bioactive glass-containing toothpaste
T2 - An in vitro study
AU - Wang, Z.
AU - Jiang, T.
AU - Sauro, S.
AU - Pashley, David Henry
AU - Toledano, M.
AU - Osorio, R.
AU - Liang, S.
AU - Xing, W.
AU - Sa, Y.
AU - Wang, Y.
PY - 2011/12
Y1 - 2011/12
N2 - Background: Dentine hypersensitivity occurs easily on exposed dentine. This study aimed to evaluate the effectiveness of a novel bioactive glass-containing toothpaste on dentine permeability and remineralization. Methods: Thirty dentine discs were divided into three groups of 10 specimens each. The groups corresponded to the following brushing treatments: no brush, distilled water, and bioactive glass-containing toothpaste (Novamin). The toothpaste was applied twice a day for 7 days. Dentine permeability was measured after ethylene-diamine-tetraacetic acid (EDTA) etching, initial application, 3-day application, 7-day application and citric acid challenge, respectively. The dentine morphology was investigated using scanning electron microscopy (SEM). Attenuated total reflection Fourier transform infrared (ATR/FTIR) spectroscopy was performed to monitor the mineral variation on demineralized dentine. Qualitative information of elemental variation before and after treatments on completely demineralized dentine was detected by energy dispersive X-ray (EDX) analysis. Results: The bioactive glass-containing toothpaste significantly reduced dentine permeability after the 7-day treatment and showed, under SEM, excellent resistance to acid challenge compared to the other groups. ATR/FTIR and EDX revealed increased mineral content after treatment with Novamin. Conclusions: As the innovative bioactive glass-containing toothpaste occlude dentinal tubules and resist acid challenge, it may be useful for the treatment of dentine hypersensitivity and dentine remineralization.
AB - Background: Dentine hypersensitivity occurs easily on exposed dentine. This study aimed to evaluate the effectiveness of a novel bioactive glass-containing toothpaste on dentine permeability and remineralization. Methods: Thirty dentine discs were divided into three groups of 10 specimens each. The groups corresponded to the following brushing treatments: no brush, distilled water, and bioactive glass-containing toothpaste (Novamin). The toothpaste was applied twice a day for 7 days. Dentine permeability was measured after ethylene-diamine-tetraacetic acid (EDTA) etching, initial application, 3-day application, 7-day application and citric acid challenge, respectively. The dentine morphology was investigated using scanning electron microscopy (SEM). Attenuated total reflection Fourier transform infrared (ATR/FTIR) spectroscopy was performed to monitor the mineral variation on demineralized dentine. Qualitative information of elemental variation before and after treatments on completely demineralized dentine was detected by energy dispersive X-ray (EDX) analysis. Results: The bioactive glass-containing toothpaste significantly reduced dentine permeability after the 7-day treatment and showed, under SEM, excellent resistance to acid challenge compared to the other groups. ATR/FTIR and EDX revealed increased mineral content after treatment with Novamin. Conclusions: As the innovative bioactive glass-containing toothpaste occlude dentinal tubules and resist acid challenge, it may be useful for the treatment of dentine hypersensitivity and dentine remineralization.
KW - Bioactive glass
KW - attenuated total reflection Fourier transformed infrared spectroscopy
KW - dentine hypersensitivity
KW - energy dispersive X-ray
KW - scanning electron microscopy
KW - toothpaste
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U2 - 10.1111/j.1834-7819.2011.01361.x
DO - 10.1111/j.1834-7819.2011.01361.x
M3 - Article
C2 - 22126346
AN - SCOPUS:82455212420
SN - 0045-0421
VL - 56
SP - 372
EP - 381
JO - Australian Dental Journal
JF - Australian Dental Journal
IS - 4
ER -