The effects of resistance training on metabolic health with weight regain

Shana O. Warner, Melissa A. Linden, Ying Liu, Benjamin R. Harvey, John P. Thyfault, Adam T. Whaley-Connell, Anand Chockalingam, Pamela S. Hinton, Kevin C Dellsperger, Tom R. Thomas

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


To determine whether resistance training effectively maintains improvements in cardiometabolic syndrome risk factors during weight regain, 9 individuals lost 4% to 6% of their body weight during an 8- to 12-week diet- and aerobic exercise-induced weight loss phase followed by a controlled weight regain phase (8-12 weeks), during which they regained approximately 50% of the lost weight while participating in a supervised resistance training program. Following weight loss (6.0%±0.3%), body mass index, body fat percentage, waist circumference, all abdominal adipose tissue depots, total cholesterol, low-density lipoprotein cholesterol, insulin, and homeostasis model assessment (HOMA) were significantly reduced, while quantitative insulin-sensitivity check index (QUICKI) and cardiorespiratory fitness (maximal oxygen consumption) significantly increased. During weight regain (48.3%±3.3% of lost weight), body fat percentage, waist circumference, and maximal oxygen consumption were maintained and muscular strength and lean body mass significantly increased. Abdominal adipose tissue depots, insulin, HOMA, and QUICKI did not significantly change after weight regain. Resistance training was effective in maintaining improvements in metabolic health during weight regain.

Original languageEnglish (US)
Pages (from-to)64-72
Number of pages9
JournalJournal of Clinical Hypertension
Issue number1
StatePublished - 2010

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine


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