The epidemiology of idiopathic dilated cardiomyopathy in a biracial community

Steven S. Coughlin, Moyses Szklo, Kenneth Baughman, Thomas A. Pearson

Research output: Contribution to journalArticlepeer-review

31 Scopus citations


An epidemiologic study of idiopathic dilated cardiomyopathy was carried out in order to identity possible risk factors for this often fatal cause of heart failure in young adults. Possible associations with black race and other genetic and environmental factors were examined by comparing newly diagnosed cases ascertained from four Baltimore hospitals (n=95) with neighborhood controls (n=95), matched on sex and 5-year age intervals. Matched and unmatched relative odds and conditional logistic regression coefficients were obtained to describe the associations. Statistically significant, independent associations were observed between idiopathic dilated cardiomyopathy and black race, low annual income, and history of asthma (p <0.05). The black predominance (relative odds=2.7, 95% confidence interval 2.0-3.4) was not explained by income, alcohol consumption, cigarette usage, body mass index, hypertension, or asthma. A possible interactive eftect was observed between black race and history of asthma and other atopic diseases. Thus, blacks, especially those with a history of hypersensitivity, may represent a high-risk subgroup in need of preventive care or early intervention.

Original languageEnglish (US)
Pages (from-to)48-56
Number of pages9
JournalAmerican journal of epidemiology
Issue number1
StatePublished - Jan 1990
Externally publishedYes


  • Alcohol, ethyl
  • Asthma
  • Blacks
  • Cardiomyopathy, congestive
  • Hypersensitivity
  • Hypertension
  • Obesity
  • Smoking

ASJC Scopus subject areas

  • Epidemiology


Dive into the research topics of 'The epidemiology of idiopathic dilated cardiomyopathy in a biracial community'. Together they form a unique fingerprint.

Cite this