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The essential role of the mitochondria-dependent death-signaling cascade in chemotherapy-induced potentiation of Apo2L/TRAIL cytotoxicity in cultured thoracic cancer cells: Amplified caspase 8 is indispensable for combination-mediated massive cell death

  • Dao M. Nguyen
  • , Wen Shuz Yeow
  • , M. Firdos Ziauddin
  • , Aris Baras
  • , Wilson Tsai
  • , Rishindra M. Reddy
  • , Alex Chua
  • , George W. Cole
  • , David S. Schrump

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Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology