The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms

Michael H. Antoni, Susan K. Lutgendorf, Steven W. Cole, Firdaus S. Dhabhar, Sandra E. Sephton, Paige Green McDonald, Michael Stefanek, Anil K. Sood

Research output: Contribution to journalReview articlepeer-review

756 Scopus citations


Epidemiological studies indicate that stress, chronic depression and lack of social support might serve as risk factors for cancer development and progression. Recent cellular and molecular studies have identified biological processes that could potentially mediate such effects. This review integrates clinical, cellular and molecular studies to provide a mechanistic understanding of the interface between biological and behavioural influences in cancer, and identifies novel behavioural or pharmacological interventions that might help improve cancer outcomes.

Original languageEnglish (US)
Pages (from-to)240-248
Number of pages9
JournalNature Reviews Cancer
Issue number3
StatePublished - Mar 2006
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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